ASSESSMENT OF THE PERFORMANCE OF THE BRAZILIAN PORTUGUESE NOTTINGHAM HEALTH PROFILE IN ADULT GROWTH HORMONE DEFICIENCY AND PULMONARY HYPERTENSION [VERSION 2; PEER REVIEW: 2 APPROVED]

Assessment of the performance of the Brazilian Portuguese Nottingham Health Profile in adult growth hormone deficiency and pulmonary hypertension [version 2; peer review: 2 approved]

Background: The Nottingham Health Profile (NHP) is a generic measure of perceived distress that has been used widely as an outcome measure in clinical practice and trials.The availability of two Brazilian datasets provided the opportunity to assess the psychometric performance of the NHP in different populations - adult growth hormone deficiency (G

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Overexpression of protein regulator of cytokinesis 1 facilitates tumor growth and indicates unfavorable prognosis of patients with colon cancer

Abstract Background Protein regulator of cytokinesis 1 (PRC1) has been reported to play important role in the pathogenesis of various cancers.However, its role in colon cancer has not been studied.Here, we aimed to investigate the biological functions and potential mechanism of PRC1 in colon cancer.Methods The expression level of PRC1 in colon canc

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